Departament de Física Aplicada
universitat politècnica de catalunya

Nonlinear Physics and Far from Equilibrium Systems

correu de contacte
   
 

Molecular motors

 
Molecular motors use chemical energy for their movement, in the presence of thermal fluctuations that, on these scales, are of a big relative magnitude. Using a simple model, based on a few relevant magnitudes, we have been able to reproduce some experimental results corresponding to a given kind of molecular motor (conventional kinesin).

 

Our goal is, by the one hand, to improve the model introducing some factors that have not been taken into account. By the other hand, extend the study to other types of molecular motors, as diosins or miosins. This is interesting not only for its biological relevance, but also for its possible applications to nanotechnology. In this way, the knowledge of the mechanism of operation of these proteins may help in the design and development of artificial nanomechanisms with similar functions.

 

 

Experiments
(K.Visscher et. al, Nature 400, 184 (1999))

Our simulations


  • Publications

    Physical analysis of a processive molecular motor: The conventional kinesin,
    A. Ciudad, A.M. Lacasta and J.M. Sancho
    Phys. Rev. E 72, 031918 (2005).
    Selected by "Virtual Journal of Biological Physics Research" as an important contribution, October 1st, 2005.


    Dynamics of an inchworm nano-walker

    A. Ciudad, J.M. Sancho and A.M. Lacasta,
    Submitted to Physica A (2005).



 
 
Secció del Departament de Física Aplicada EPSEB
Av. Dr. Marañón 44 - 08028 Barcelona - Tel.: 93-401 62 63 - blas@fa.upc.edu